Multiple Sclerosis - MS LifeLines
I wish there was an effective treatment to help me fight my relapsing MS.
Stop wishing.
Start learning more about Rebif.
Ask your doctor if Rebif is right for you.
About Rebif® (interferon beta-1a)
- 1 vs. 14 Steps to Prep: Rebif vs. Betaseron® (interferon beta-1b)
- See how Rebif compares to other therapies for relapsing MS.
- Comparing Treatments
- See how Rebif compares to other therapies for relapsing MS.
- Effectiveness of Rebif 44mcg vs. Avonex
- Review the data from an important clinical trial.
- Worried about the cost of your MS therapy?
- Find out how to get help
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Programs
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What's New
- Looking for ways to minimize stress during the holidays?
- Interested in chatting live online with someone from MS LifeLines?
We want your feedback! - Talk MS web episode "Staying Focused: MS and the Eye"
- Your Questions Answered. Watch videos and read responses from MS experts and others
- Insurance co-pay too high (more than $50/month)? MS LifeLines may be able to help.
Betaseron is a registered trademark of Bayer HealthCare Pharmaceuticals Inc.
Avonex is a registered trademark of Biogen Idec.
Brought to you by EMD Serono, Inc. and Pfizer Inc, the co-marketers of Rebif® (interferon beta-1a) in the US 

Prescribing Information - Medication Guide
This information is intended only for residents of the United States.
Rebif is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS. Efficacy has been established in controlled studies up to 2 years in duration. Rebif is not approved for the treatment of chronic progressive multiple sclerosis. Rebif is available by prescription only in 22 mcg and 44 mcg pre-filled syringes and a titration pack.
Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif. Let your doctor know if you have a history of depression, seizures, liver disease, thyroid problems, and blood count or bleeding problems or if you have had previous allergic reactions to medications. Tell your doctor about all medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Rebif and other medicines may affect each other causing serious side effects. Talk to your doctor before you take any new medicines. Rebif is not recommended for women who are or plan to become pregnant.
Potential serious side effects of Rebif include depression, liver problems, risk to pregnancy, injection site problems and severe allergic reactions. Allergic reactions are rare and may be associated with difficulty breathing and loss of consciousness, which requires immediate medical attention.
The most common side effects with Rebif are injection site reactions, flu-like symptoms (fever, chills, muscle aches, tiredness), depression, abdominal pain, increased liver enzymes, and blood cell count decreases. Let your doctor know immediately if you have any of these symptoms or feel sad, tired, hot or cold, experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
This information is not intended to replace discussions with your healthcare provider. For additional information about Rebif, please consult the Medication Guide or Prescribing Information and talk to your doctor. You can also call toll free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.
MS LifeLines is an educational support service for people living with MS and their families. MS LifeLines and MS LifeLines Ambassadors are sponsored by EMD Serono, Inc. and Pfizer Inc.
Rebif, Rebiject II and MS LifeLines are registered trademarks and the Rebif logo is a trademark of EMD Serono, Inc. or its affiliates.
MS in Balance Your Life in Full is a service mark of EMD Serono, Inc. or its affiliates.
Copyright 2009 EMD Serono, Inc. All rights reserved.