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Multiple Sclerosis - MS LifeLines

An educational and supportive community for people living with multiple sclerosis.

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"The best piece of advice that I've received to manage my MS is to take care of myself."

Jacqueline — MS LifeLines® Nurse Specialist

Jacqueline has been an MS LifeLines call center nurse for the past three years. With 36 years in nursing, spanning five specialties, Jacqueline now finds her fulfillment in devoting her life to helping MS patients manage their lives after diagnosis. Jacqueline is all about quality of life, and helping those living with relapsing MS achieve it. What particularly impresses her, she says, is "the perseverance of MS patients who have struggled and the nurses who never leave their sides."

Jacqueline traces her nursing aspirations to the compassion of her mother, who cared for an elderly woman when Jacqueline was a child. That compassion continues to drive Jacqueline today as she listens to patients' stories, asks how they're doing with their Rebif® (interferon beta-1a) therapy, and how they're managing their lives – all in service of sharing techniques and strategies that can help.

"One time I was talking with a young mother of three children who was upset and crying because weakness in her legs was preventing her from carrying her baby around as the day went on. We talked awhile and came up with different ways she could conserve her energy, such as limiting certain household chores and setting up a board to better organize her schedule. She was so grateful!"

Jacqueline urges patients to stay in the present, to deal with what's needed today, and not to try to take in too much at once. She also encourages them not to be too hard on themselves. "I try to have them take time every day to do something kind for themselves," she says. "And call MS LifeLines. We can help you through the process!"

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Brought to you by EMD Serono, Inc. and Pfizer Inc, the co-marketers of Rebif® (interferon beta-1a) in the US EMD SeronoPfizer

Prescribing Information - Medication Guide

This information is intended only for residents of the United States.

Indication

Rebif is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS. Rebif is not approved for treatment of chronic progressive MS. Rebif is available in 22 mcg and 44 mcg prefilled, preassembled syringes and a titration pack by prescription only.

Important Safety Information

Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif. Let your doctor know if you have a history of depression, seizures, liver disease, thyroid problems, or blood cell count or bleeding problems, or if you have had previous allergic reactions to medications. Tell your doctor about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Rebif and other medicines may affect each other causing serious side effects. Talk to your doctor before you take any new medicines. Rebif is not recommended for women who are or plan to become pregnant.

Potential serious side effects of Rebif include depression and risk of suicide, liver problems, risk to pregnancy, injection-site problems, and severe allergic reactions. Allergic reactions are rare and may be associated with difficulty in breathing and loss of consciousness, which require immediate medical attention.

The most common side effects with Rebif are injection-site reactions, flu-like symptoms (fever, chills, muscle aches, tiredness), depression, abdominal pain, increased liver enzymes, and blood cell count decreases. Let your doctor know if you have any of these symptoms or feel sad, tired, hot or cold, or experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).

Compared with Avonex, side effects were generally similar despite the higher, more frequent dosing of Rebif. Differences included people taking Avonex had more flulike symptoms than those taking Rebif. People taking Rebif had a greater number of injection-site reactions, elevated liver enzymes, and decreased white blood cell counts; these events also occurred more frequently with Rebif posttransition versus prior use of Avonex.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

This information is not intended to replace discussions with your doctor. For additional information about Rebif, please consult the Prescribing Information and Medication Guide and talk to your doctor. You can also visit www.mslifelines.com or call toll-free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.

MS LifeLines is an educational support service for people living with MS and their families. MS LifeLines and MS LifeLines Ambassadors are sponsored by EMD Serono, Inc. and Pfizer Inc.

Rebif, Rebiject II and MS LifeLines are registered trademarks and the Rebif logo is a trademark of EMD Serono, Inc. or its affiliates.

MS in Balance Your Life in Full is a service mark of EMD Serono, Inc. or its affiliates.

Copyright 2010 EMD Serono, Inc. All rights reserved.