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"The best piece of advice that I've received to manage my MS is to take care of myself."

Shiela, MS LifeLines Ambassador

Living with RRMS since 2002

Taking Rebif® since 2003

Julie — MS LifeLines® Nurse Specialist

— Julie, RN, MSCN

Julie, an MS LifeLines Nurse specialist since 2003, says she tries to make a difference every day. Julie tries to help not only patients on Rebif® (interferon beta-1a) therapy, but others in their lives, as well. "We need to be very careful and really listen to what else is going on in their homes," she says. Julie finds strengthening the bond between MS patients and their care partners particularly rewarding.

"There are many days that patients or their caregivers have told me that I called at just the right time. One patient was crying because she missed some injections and hadn't been motivated to continue treatment. She just needed someone to talk to and get back on track. She wasn't aware of some of the resources and management tips that can make a huge difference."

Believing firmly in the mind-body connection, Julie tries to help patients get their day-to-day affairs organized, so their minds are free and can stay strong. "I listen to what the real issues are and guide them to resources like financial help, counseling, and resources such as respite for care givers." She also reminds patients of the importance of keeping their neurologist and PCP informed.

With 21 years in nursing, Julie's many years of experience help her to listen and guide patients she talks with in the right direction. She lives by a simple motto: "Yesterday is history, tomorrow is a mystery, and the present is a special gift." Julie's gift to MS patients is hope.

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Brought to you by EMD Serono, Inc. and Pfizer Inc., the co-marketers of Rebif® (interferon beta-1a) in the US EMD SeronoPfizer

Prescribing Information - Medication Guide

This information is intended only for residents of the United States.

Rebif is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS. Rebif is not approved for the treatment of chronic progressive multiple sclerosis. Rebif is available by prescription only in 22 mcg and 44 mcg pre-filled syringes and a titration pack.

Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif. Let your doctor know if you have a history of depression, seizures, liver disease, thyroid problems, and blood count or bleeding problems or if you have had previous allergic reactions to medications. Tell your doctor about all medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Rebif and other medicines may affect each other causing serious side effects. Talk to your doctor before you take any new medicines. Rebif is not recommended for women who are or plan to become pregnant.

Potential serious side effects of Rebif include depression, liver problems, risk to pregnancy, injection site problems and severe allergic reactions. Allergic reactions are rare and may be associated with difficulty breathing and loss of consciousness, which requires immediate medical attention.

The most common side effects with Rebif are injection site reactions, flu-like symptoms (fever, chills, muscle aches, tiredness), depression, abdominal pain, increased liver enzymes, and blood cell count decreases. Let your doctor know immediately if you have any of these symptoms or feel sad, tired, hot or cold, experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

This information is not intended to replace discussions with your healthcare provider. For additional information about Rebif, please consult the Medication Guide or Prescribing Information and talk to your doctor. You can also call toll free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.

MS LifeLines is an educational support service for people living with MS and their families. MS LifeLines and MS LifeLines Ambassadors are sponsored by EMD Serono, Inc. and Pfizer Inc.

Rebif, Rebiject II, and MS LifeLines are registered trademarks of EMD Serono, Inc. or its affiliates.

MS in Balance is a service mark of EMD Serono, Inc. or its affiliates.

Copyright 2008 EMD Serono, Inc. All rights reserved.