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Multiple sclerosis (MS) therapy:
Rebif® (interferon beta-1a)

Choosing a therapy that's right for you

When you and your doctor choose a disease-modifying drug (DMD) to treat your relapsing MS, you want to choose a multiple sclerosis therapy that's been proven effective and has a well-established safety profile.

You may also want to consider a therapy that offers features designed for convenient administration and a comprehensive support service that includes patient assistance programs, MS education and therapy support.

Consider Rebif

Proven effective: Rebif is the only self-injected relapsing MS therapy that is proven to work across all 3 key treatment goals of MS: slowing disability progression, reducing relapse rate, and reducing the development of new, active brain lesions.

The exact correlation between MRI findings and the current or future clinical status of patients, including disability progression, is unknown.

Rebif is used to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with relapsing forms of MS. Rebif is not approved for the treatment of chronic progressive MS. Rebif is available in 22 mcg and 44 mcg prefilled, preassembled syringes and a titration pack by prescription only.

Please see important safety information below and Rebif Medication Guide and Prescribing Information in the top right corner of this website, and speak with your doctor for more information.

Well-established safety profile: You can feel confident that the safety profile of Rebif is backed by 16 years of clinical trial and patient experience.

Administration options: Rebif offers administration options and product features that are designed for convenience.

Affordable access: Through the MS LifeLines Access Made Simple program, you may be eligible to receive Rebif for no cost or for no more than $50 per month, regardless of your insurance or income and with no limit on assistance. For example, if you have no insurance, no drug coverage or partial drug coverage and are starting or restarting Rebif, you may be eligible to receive 1 year of FREE Rebif medication at no cost, without having to meet financial requirements or verify income for eligibility.

Learn more about MS LifeLines Access Made Simple eligibility requirements.

Some limitations are required by law. People residing in certain states, as well as those covered by federal and state programs, may not be eligible for assistance. Program eligibility requirements and benefits subject to change and discontinuation at any time.

Nursing support: When you take Rebif, you're not alone. The MS LifeLines® Nurse Network is with you every step of the way, from answering certain questions by telephone about relapsing MS and Rebif to helping you get started taking Rebif by providing in-home injection training and more.

Learn more about the benefits of Rebif therapy for multiple sclerosis:

Remember, Rebif gives you more than an effective treatment for relapsing MS—it connects you to a network of support here to help you every step of the way.

Indication

  • Rebif is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS.
  • Rebif is not approved for treatment of chronic progressive MS.
  • Rebif is available in 22 mcg and 44 mcg prefilled, preassembled syringes and a titration pack by prescription only.

Important Safety Information

Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif.

Let your doctor know:

  • If you have a history of depression, seizures, liver disease, thyroid problems, or blood cell count or bleeding problems, or if you have had previous allergic reactions to medications.
  • About all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Rebif and other medicines may affect each other, causing serious side effects.
  • Before you take any new medicines.

Rebif is not recommended for women who are or plan to become pregnant.

Potential serious side effects of Rebif include:

  • Depression and risk of suicide
  • Liver problems
  • Risk to pregnancy
  • Injection-site problems
  • Severe allergic reactions. Allergic reactions are rare and may be associated with difficulty in breathing and loss of consciousness, which require immediate medical attention.

The most common side effects with Rebif are:

  • Injection-site reactions
  • Flu-like symptoms (fever, chills, muscle aches, tiredness)
  • Depression
  • Abdominal pain
  • Increased liver enzymes
  • Blood cell count decreases

Let your doctor know if you have any of these symptoms or feel sad, tired, hot or cold, or experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

This information is not intended to replace discussions with your doctor. For additional information about Rebif, please consult the Prescribing Information and Medication Guide and talk to your doctor. You can also call toll-free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.

MS LifeLines is an educational support service for people living with MS and their families. MS LifeLines and MS LifeLines Ambassadors are sponsored by EMD Serono, Inc. and Pfizer Inc. Speakers and MS LifeLines Ambassadors who participate in Talk MS or in live events are sponsored by EMD Serono, Inc. and Pfizer Inc. UNIQUELY [you] is a service mark of EMD Serono, Inc. or its affiliates. Rebif, Rebiject II and MS LifeLines are registered trademarks and the Rebif logo is a trademark of EMD Serono, Inc. or its affiliates.

This information is intended only for residents of the United States.

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