Multiple Sclerosis - MS LifeLines
I wish my relapsing MS therapy fit my lifestyle
Treatment Differences
Rebif offers flexibility and convenience
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- Watch how Rebif saves you 13 steps of preparation vs Betaseron® (interferon beta-1b).
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Take a video tour of MS LifeLines.
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- Hear from Vickie about how the
MS LifeLines Access Made Simple program helped her get affordable access to Rebif for the treatment of her relapsing MS. -
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- Rebif Injection Training Video
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- View How Rebif (interferon beta-1a) Works
Find out how Rebif can help slow the progression of your relapsing MS. -
- MOA
- Find new ways to accommodate your day-to-day needs. Watch other interviews
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- Shiela_01
- What was the most compelling reason to choose Rebif for your relapsing MS therapy? Watch other interviews
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- Juli
- Watch as Kellie talks about her MRI lesion load. Watch other interviews
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- Kellie
- Shiela shares insights about communication with her daughter about MS. Watch other interviews
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- Shiela
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- Elizabeth
- Take a sneak peek at our next program.
Register now -
- CHOOSE_THERAPY
- Watch how Rebif saves you 13 steps of preparation vs Betaseron® (interferon beta-1b).
-
- why_rebif
- Meet the MS LifeLines Team
Take a video tour of MS LifeLines.
Mire este vídeo en español. -
- MTV
- Access Made Simple Program
-
- AMS_MTV_short
- Hear from Vickie about how the
MS LifeLines Access Made Simple program helped her get affordable access to Rebif for the treatment of her relapsing MS. -
- AMS_MTV_long
- Conozca al equipo de MS LifeLines
Realice un tour en video por MS LifeLines. -
- ES_MTV
-
- bike
- Rebif Injection Training Video
Mire este vídeo en español. -
- RITV
- Video de entrenamiento sobre la inyección de Rebif
-
- ES_RITV
- View How Rebif (interferon beta-1a) Works
Find out how Rebif can help slow the progression of your relapsing MS. -
- MOA
- Find new ways to accommodate your day-to-day needs. Watch other interviews
-
- Shiela_01
- What was the most compelling reason to choose Rebif for your relapsing MS therapy? Watch other interviews
-
- Juli
- Watch as Kellie talks about her MRI lesion load. Watch other interviews
-
- Kellie
- Shiela shares insights about communication with her daughter about MS. Watch other interviews
-
- Shiela
-
- Elizabeth
- The only interferon beta available in a prefilled, preassembled, and ready-to-use syringe, so no premixing or assembly is required
- The Rebiject® II auto-injector can help make injections easier than with manual injection
- The 3-times weekly dosing schedule allows for injection-free weekends
Rebif has 209 fewer injections per year than Copaxone® (glatiramer acetate injection)
Rebif is less than half the size of an Avonex® needle
A 25-gauge, 1" needle for intramuscular injection may be substituted for the 23-gauge, 1½" needle by the prescribing physician, if deemed appropriate. The higher the gauge, the thinner the needle. Although needles are shown to scale, they are not actual size.
Redness, pain or swelling at the injection site can occur with any injectable treatment.
This quote reflects the personal experience of one person, and others can be different. Results and experiences vary from patient to patient. It is best to contact your doctor to discuss what's best for you. Mike is an MS LifeLines Ambassador and has chosen to share his story with other people living with MS.
How do interferon therapies differ?
What's the difference between interferon-beta therapies used to treat relapsing MS?
Each interferon-beta therapy differs by:
- Where it is given (injected under the skin or into the muscle)
- How much is given (high vs low dose)
- How often it is taken (frequency)
The benefits of higher dose, more frequent interferon therapy
Rebif 44 mcg is a high-dose, high-frequency interferon-beta therapy, while Avonex is a lower dose interferon beta therapy that is taken less frequently. The three-times-weekly injection schedule of Rebif maintains a constant level of interferon beta-1a in your body. With the once-weekly injection schedule of Avonex, the level of interferon beta-1a fades throughout the week and is gone from your body 3 days before your next injection.
Over an average of 64 weeks in the EVIDENCE study*, Rebif 44 mcg given 3 times a week was shown to work better when compared to Avonex 30 mcg given once a week for:
- Reducing brain lesion activity on MRI
- Preventing relapses over an average of 64 weeks
Rebif is the only therapy for relapsing MS that has been proven to work better than another therapy in a Class I Trial**.
Read more about the EVIDENCE study.
This reflects the personal experience of one person, and others can be different. Results and experiences vary from patient to patient. It is best to contact your doctor to discuss what's best for you. Gary is an MS LifeLines Ambassador, and he and Kathy have chosen to share his story with other people living with MS.
Please note that the exact correlation between MRI findings and the current or future clinical status of patients, including disability progression, is unknown.
Please see the Rebif Medication Guide and speak with your doctor for more information.
Avonex is a registered trademark of Biogen Idec.
Copaxone is a registered trademark of Teva Neuroscience, Inc.
Betaseron is a registered trademark of Bayer HealthCare Pharmaceuticals Inc.
* EVidence for Interferon Dose-response: European North American Comparative Efficacy.
** According to the American Academy of Neurology, the data in a Class I Trial is collected under the highest scientific standards.

