Forgot password?

"One day, one wonderful hour at a time."

Depression

Depression or Mood Swings

Depression is a widespread problem, occurring not just in people who have MS. It's important to understand that depression is a term used broadly when it comes to people with MS. It is often used to describe a wide range of emotions, from feeling down for a few hours one day, to clinical depression, which may last for months. People with MS, as well as their friends and family, need to know that depression, in whatever form, is common.

Call MS LifeLines® toll free 1-877-447-3243. Our reimbursement specialists are available to answer your questions Monday through Friday, 8 am to 8 pm ET. Our MS-certified nurses are available to answer your questions Monday through Friday, 8 am to 10 pm ET.

Call MS LifeLines Today!

Depression does not mean that you are "weak." You should not feel ashamed about being depressed or feel the need to hide it. You cannot control or prevent depression.

We still do not fully understand the nature of depression in MS. But, in recent years, we have learned much about it:

  • Stress is a major factor in depression. The stress of dealing with a diagnosis of a chronic disease, and the possibility of disability can bring on depression.
  • The disease process of MS may cause depression. If MS damages areas of the brain that are involved in emotional expression and control, a variety of behavioral changes can result, including depression.
  • Depression may also be associated with MS-related changes that occur in the immune or neuroendocrine systems.
  • Depression can also be a side effect of some medications.

People with MS often go through a period of grieving. They may grieve the losses they experience due to MS, such as walking or working. This mourning may look like depression. Grief eventually goes away on its own. So, it's important to recognize the differences between mild, everyday "depression"; grief; and clinical depression. Clinical depression is a serious condition that can last from at least 2 weeks to several months. It produces flare-ups known as "episodes."

Learn about dealing with depression

Brought to you by EMD Serono, Inc. and Pfizer Inc., the co-marketers of Rebif® (interferon beta-1a) in the US EMD SeronoPfizer

Prescribing Information - Medication Guide

This information is intended only for residents of the United States.

Rebif is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS. Rebif is not approved for the treatment of chronic progressive multiple sclerosis. Rebif is available by prescription only in 22 mcg and 44 mcg pre-filled syringes and a titration pack.

Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif. Let your doctor know if you have a history of depression, seizures, liver disease, thyroid problems, and blood count or bleeding problems or if you have had previous allergic reactions to medications. Tell your doctor about all medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Rebif and other medicines may affect each other causing serious side effects. Talk to your doctor before you take any new medicines. Rebif is not recommended for women who are or plan to become pregnant.

Potential serious side effects of Rebif include depression, liver problems, risk to pregnancy, injection site problems and severe allergic reactions. Allergic reactions are rare and may be associated with difficulty breathing and loss of consciousness, which requires immediate medical attention.

The most common side effects with Rebif are injection site reactions, flu-like symptoms (fever, chills, muscle aches, tiredness), depression, abdominal pain, increased liver enzymes, and blood cell count decreases. Let your doctor know immediately if you have any of these symptoms or feel sad, tired, hot or cold, experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

This information is not intended to replace discussions with your healthcare provider. For additional information about Rebif, please consult the Medication Guide or Prescribing Information and talk to your doctor. You can also call toll free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.

MS LifeLines is an educational support service for people living with MS and their families. MS LifeLines and MS LifeLines Ambassadors are sponsored by EMD Serono, Inc. and Pfizer Inc.

Rebif, Rebiject II, and MS LifeLines are registered trademarks of EMD Serono, Inc. or its affiliates.

MS in Balance is a service mark of EMD Serono, Inc. or its affiliates.

Copyright 2008 EMD Serono, Inc. All rights reserved.